In vivo imaging of microvasculature in human finger skin using SV-OCT

Abstract Speckle variance optical coherence tomography (SV-OCT) enables non-invasive visualization of the three-dimensional vascular information within the microcirculatory tissue bed by utilizing flowing red blood cells as intrinsic contrast agents, without the need for dye injection. This study evaluated the feasibility of using the SV-OCT device for monitoring the microvascular system in human finger skin. An adaptive wavelet Fourier transform filtering algorithm was applied to remove stripe noise from the images of finger vasculature. The results demonstrate that SV-OCT systems can be used to extract the vascular system of finger skin. By employing an adaptive wavelet Fourier transform filtering (AWFTF)algorithm to process the vascular data, stripe noise can be effectively removed, thereby enhancing the imaging quality of the blood vessels.