Bioactive components in prunella vulgaris for treating Hashimoto's disease via regulation of innate immune response in human thyrocytes
Quercetin, luteolin, kaempferol, morin, and β-sitosterol reproduced an anti-inflammatory and anti-apoptosis effect of <i>PV</i> in stimulated human thyrocytes, which potentially contributed to the treatment efficacy of <i>PV</i> in HT.
Authors
- Bo Jiang (ORCID: https://orcid.org/0000-0002-1577-7272)
- Yuqian Luo (ORCID: https://orcid.org/0000-0003-2792-488X)
- Yanxue Wang (ORCID: https://orcid.org/0000-0001-8739-4740)
- Fei Chen (ORCID: https://orcid.org/0000-0003-3895-6318)
- Xitai Sun (ORCID: https://orcid.org/0000-0001-9679-0171)
- Yongzhao Chen
- Cheng Qu (ORCID: https://orcid.org/0009-0003-8332-6929)
- Chaoyu Jiang
- Lei Su
- Chen Zhang (ORCID: https://orcid.org/0000-0003-0721-5648)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Drum Tower Hospital (CN)
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e36103
- Citations
- 5
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.17