Synthesis and Evaluation of Antibacterial and Antifungal Activities <i>In vitro</i> and <i>In silico</i> of Novel Morpholinoalkoxychalcones
The <i>in silico</i> study has revealed two targets to align with the <i>in vitro</i> results. Longer alkyl chains have enhanced the activity, along with the presence of OH, NH<sub>2</sub>, and halogen groups on both rings A and B.
Authors
- Khac‐Minh Thai (ORCID: https://orcid.org/0000-0002-5279-9614)
- Trương Thị Bích Phượng (ORCID: https://orcid.org/0000-0002-8049-8499)
- Tan Thanh Mai (ORCID: https://orcid.org/0000-0001-7313-9853)
- P. Huynh (ORCID: https://orcid.org/0009-0005-8695-794X)
- Thành Đạo Trần
- Thinh Nguyen Quang Don
- Đỗ Thị Thanh
- Hoang Minh Phan
Institutions
- University of Medicine and Pharmacy at Ho Chi Minh City (VN)
Publication Details
- Journal
- Medicinal Chemistry
- Published
- 2024-08-12
- DOI
- https://doi.org/10.2174/0115734064316022240801093905
- Citations
- 1
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.25