Systematic reviews of clinical laboratory studies: Pilot risk of bias tool developed by consensus
The plethora of COVID-19 research has highlighted the need for formal methods to systematically appraise clinical laboratory studies related to disease pathology. This tool provides a systematic approach to appraise the validity of these studies. Our process may guide others in the development of appraisal tools in areas where they are needed. Given the relationship between clinical laboratory studies and the development of medical treatments, further development of this risk of bias tool is important for evidence-based healthcare and research.
Authors
- Rebecca Kuehn (ORCID: https://orcid.org/0000-0003-4556-1752)
- Paul Garner (ORCID: https://orcid.org/0000-0002-0607-6941)
- Robert A.S. Ariëns (ORCID: https://orcid.org/0000-0002-6310-5745)
- Beverley J. Hunt (ORCID: https://orcid.org/0000-0002-4709-0774)
- Greg J. Towers (ORCID: https://orcid.org/0000-0002-7707-0264)
- Tilly Fox (ORCID: https://orcid.org/0000-0003-3627-1016)
- Robert Lever
Institutions
- University of Leeds (GB)
- Liverpool School of Tropical Medicine (GB)
- Kings Health Partners (GB)
- University College London (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Cochrane Evidence Synthesis and Methods
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1002/cesm.12098
- Citations
- 4
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- Government of the United Kingdom
- Medical Research Council