Genetic Variants in p53 Pathway Genes Affect Survival of Patients with HBV-Related Hepatocellular Carcinoma
We identified two observed survival-associated SNPs in <i>CD82</i> and <i>PMAIP1</i> in the p53 pathway, which influenced HBV-HCC survival possibly through a mechanism of altering mRNA expression. Large studies are warranted to validate our findings.
Authors
- Liming Qin (ORCID: https://orcid.org/0000-0003-4263-301X)
- Hongping Yu (ORCID: https://orcid.org/0000-0002-6128-0398)
- Qian Guo (ORCID: https://orcid.org/0000-0002-1211-6436)
- Qiuling Lin
- Cunli Nong
- Shuyan Liu (ORCID: https://orcid.org/0000-0002-6948-5734)
- Yizhen Gong (ORCID: https://orcid.org/0000-0002-6236-8340)
- Zihan Zhou (ORCID: https://orcid.org/0000-0003-1444-4713)
- Qiongguang Huang
- Moqin Qiu (ORCID: https://orcid.org/0000-0001-5253-9081)
- Qiuping Wen
- Xiaoxia Wei (ORCID: https://orcid.org/0000-0003-2443-1203)
- Xiumei Liang
- Yingchun Liu (ORCID: https://orcid.org/0000-0002-4531-6565)
- Ji Cao (ORCID: https://orcid.org/0000-0003-2813-6404)
- Yuying Wei (ORCID: https://orcid.org/0009-0000-5581-4747)
- Peiqin Chen (ORCID: https://orcid.org/0009-0003-4013-8194)
- Jingmei Tang
- Yanji Jiang
Institutions
- Guangxi Medical University (CN)
- Liuzhou Maternal and Child Health Hospital (CN)
- Fourth Affiliated Hospital of Guangxi Medical University (CN)
- Guangxi Center for Disease Prevention and Control (CN)
Publication Details
- Journal
- Journal of Hepatocellular Carcinoma
- Published
- 2024-08-01
- DOI
- https://doi.org/10.2147/jhc.s459792
- Citations
- 2
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Natural Science Foundation of Guangxi Province
- Guangxi Medical University
- Guangxi University