Anxiety-like Characteristics, Forepaw Thermal Sensitivity Changes and Glial Alterations 1 Month After Repetitive Blast Traumatic Brain Injury in Male Rats
Data from this initial preclinical study support the prevalence of putative anxiety-like behaviour, enhancement in forepaw thermal sensitivity and increase in the number of glial cells even 1 month after rbTBI. These findings have potential implications in the treatment evaluation of blast-exposed military and civilian populations and emphasise the need for devising protective measures for people susceptible to single or repeated exposures. A greater further understanding of rbTBI-related chronic concurrent behavioural and neuropathological sequela is warranted.
Authors
- Shane A. Perrine (ORCID: https://orcid.org/0000-0001-6983-2372)
- Srinivasu Kallakuri (ORCID: https://orcid.org/0000-0002-4681-6350)
- Cameron Davidson (ORCID: https://orcid.org/0000-0001-7932-6262)
- Cynthia Bir (ORCID: https://orcid.org/0000-0002-0777-0951)
- Alana C. Conti (ORCID: https://orcid.org/0000-0003-1384-4950)
- Nareen Sadik (ORCID: https://orcid.org/0000-0002-0501-7560)
- Kelly E. Bosse
- Ali Gheidi
Institutions
- Mercer University (US)
- Oakland University (US)
- Wayne State University (US)
- John D. Dingell VA Medical Center (US)
Publication Details
- Journal
- Annals of Neurosciences
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1177/09727531241248976
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- National Institutes of Health