Choriocapillaris Loss in a Pediatric Patient With Congenital Cytomegalovirus Seen on Optical Coherence Tomography Angiography

<b>Purpose:</b> To describe choriocapillaris loss on optical coherence tomography angiography (OCTA) imaging in a pediatric patient with congenital cytomegalovirus (CMV). <b>Methods:</b> A case was evaluated. <b>Results:</b> A 7-year-old female patient was referred for retinal evaluation of maculopathy in the right eye. She was diagnosed with congenital CMV at 14 months of age, at which time treatment was not deemed necessary. At 7 years of age, the patient was asymptomatic with 20/20 Snellen visual acuity. Funduscopy and colored fundus photographs showed macular scarring. Ancillary testing was performed, with retinal pigment epithelium alterations and disruption of the outer retinal layers seen on OCT and choriocapillaris loss in the area of the macular scar seen on OCTA. <b>Conclusions:</b> For patients with congenital CMV, OCTA imaging can show significant changes in choriocapillaris function. These changes do not necessarily correlate with visual function parameters. OCTA may be useful as an additional screening or surveillance modality for patients with congenital CMV or CMV retinitis.

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Publication Details

Journal
Journal of VitreoRetinal Diseases
Published
2024-08-12
DOI
https://doi.org/10.1177/24741264241271707
Citations
2
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.77

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article

Choriocapillaris Loss in a Pediatric Patient With Congenital Cytomegalovirus Seen on Optical Coherence Tomography Angiography

Nimesh A. Patel, Sandra Hoyek, Lindsay K. Kozek
2 citations
Journal of VitreoRetinal Diseases
Cytomegalovirus and herpesvirus research
0.77
article

Choriocapillaris Loss in a Pediatric Patient With Congenital Cytomegalovirus Seen on Optical Coherence Tomography Angiography

Nimesh A. Patel, Sandra Hoyek, Lindsay K. Kozek
article en
2 citations

Abstract

<b>Purpose:</b> To describe choriocapillaris loss on optical coherence tomography angiography (OCTA) imaging in a pediatric patient with congenital cytomegalovirus (CMV). <b>Methods:</b> A case was evaluated. <b>Results:</b> A 7-year-old female patient was referred for retinal evaluation of maculopathy in the right eye. She was diagnosed with congenital CMV at 14 months of age, at which time treatment was not deemed necessary. At 7 years of age, the patient was asymptomatic with 20/20 Snellen visual acuity. Funduscopy and colored fundus photographs showed macular scarring. Ancillary testing was performed, with retinal pigment epithelium alterations and disruption of the outer retinal layers seen on OCT and choriocapillaris loss in the area of the macular scar seen on OCTA. <b>Conclusions:</b> For patients with congenital CMV, OCTA imaging can show significant changes in choriocapillaris function. These changes do not necessarily correlate with visual function parameters. OCTA may be useful as an additional screening or surveillance modality for patients with congenital CMV or CMV retinitis.

Journal of VitreoRetinal DiseasesVol. 8(6)
Massachusetts Eye and Ear Infirmary (US), Boston Children's Hospital (US), Harvard University (US)
Massachusetts Eye and Ear
Good health and well-being
Openalex Percentile: Top 26%
Cytomegalovirus and herpesvirus research
0.77
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