Evaluation of prescribing patterns of switching to and add-on lemborexant in patients treated with hypnotic medication: a nationwide claims database study in Japan

The proportion of successful switching was higher in patients who switched to lemborexant than in those who added lemborexant as a concomitant treatment. The lower success proportion in the add-on cohort might be related to clinically more severe insomnia, and/or a concomitant prescription of benzodiazepine or non-benzodiazepine, from which discontinuation may be challenging.

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Publication Details

Journal
Expert Opinion on Pharmacotherapy
Published
2024-08-12
DOI
https://doi.org/10.1080/14656566.2024.2392018
Citations
3
Primary Topic
Sleep and related disorders
Type
article
Field-Weighted Citation Impact
1.52
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article

Evaluation of prescribing patterns of switching to and add-on lemborexant in patients treated with hypnotic medication: a nationwide claims database study in Japan

Kayoko Mizuno, Kazuo Mishima, Koji Kawakami, Takehiro Taninaga et al.
3 citations
Expert Opinion on Pharmacotherapy
Sleep and related disorders
1.52
article

Evaluation of prescribing patterns of switching to and add-on lemborexant in patients treated with hypnotic medication: a nationwide claims database study in Japan

Kayoko Mizuno, Kazuo Mishima, Koji Kawakami, Takehiro Taninaga, Sachiko Tanaka‐Mizuno, Margaret Moline, Yukinori Sakata, Mika Ishii, Satomi Yoshida, Kenichi Fujimoto, Naoki Kubota, Toshiki Fukasawa
article en
3 citations

Abstract

The proportion of successful switching was higher in patients who switched to lemborexant than in those who added lemborexant as a concomitant treatment. The lower success proportion in the add-on cohort might be related to clinically more severe insomnia, and/or a concomitant prescription of benzodiazepine or non-benzodiazepine, from which discontinuation may be challenging.

Expert Opinion on PharmacotherapyVol. 25(12)
University of Tsukuba (JP), Kobe Pharmaceutical University (JP), Akita University (JP), Kyoto University (JP), Eisai (United States) (US), Eisai (Japan) (JP)
Openalex Percentile: Top 17%
Sleep and related disorders
1.52
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