Insomnia and sleep duration for kidney function: Mendelian randomization study
This study demonstrates a causal impact of insomnia on the risk of elevated serum creatinine and a positive effect of sleep duration on serum creatinine, eGFRcys, and cystatin C. Our findings also suggest their potential indirect effects on ARF, CRF, microalbuminuria, and β2 microglobulin mediated by obesity.
Authors
- Zuofu Tang (ORCID: https://orcid.org/0009-0002-8121-3632)
- Ruojiao Wang
- Zhaozhong Zhong
- Ning Na (ORCID: https://orcid.org/0000-0001-8623-9837)
- Jinhua Zhang (ORCID: https://orcid.org/0000-0002-5629-0348)
- Jiaqing Wu (ORCID: https://orcid.org/0000-0002-5358-5845)
- Yang Zhang (ORCID: https://orcid.org/0000-0002-3588-4702)
Institutions
- Sun Yat-sen University (CN)
- Wenzhou Medical University (CN)
- Quzhou City People's Hospital (CN)
- Key Laboratory of Guangdong Province (CN)
- Quzhou University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1080/0886022x.2024.2387430
- Citations
- 7
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 7.76
Funders
- National Natural Science Foundation of China