Regimen on <i>Dnaja3</i> haploinsufficiency mediated sarcopenic obesity with imbalanced mitochondrial homeostasis and lipid metabolism
Muscular Dnaja3 haploinsufficiency dysregulates mitochondrial function and lipid metabolism then leads to sarcopenic obesity. GMI emerges as a therapeutic regimen for sarcopenic obesity treatment through DNAJA3 activation.
Authors
- Yeou‐Guang Tsay (ORCID: https://orcid.org/0000-0001-6511-9158)
- Chen‐Chung Liao (ORCID: https://orcid.org/0000-0002-6634-8355)
- Yu‐Ning Fann
- Jeng‐Fan Lo (ORCID: https://orcid.org/0000-0001-7188-9140)
- Tung‐Fu Huang
- Hsin‐Chen Lee (ORCID: https://orcid.org/0000-0001-7455-9593)
- Wan‐Huai Teo
Institutions
- National Yang Ming Chiao Tung University (TW)
- Taipei Veterans General Hospital (TW)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1002/jcsm.13549
- Citations
- 2
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.65
Funders
- Chang Gung University
- Chang Gung Medical Foundation
- Taipei Veterans General Hospital
- National Science and Technology Council