Paired organoids from primary gastric cancer and lymphatic metastasis are useful for personalized medicine
The organoid lines recapitulate the drug sensitivity of the parental tissues. The paired organoid lines present a step-change toward living biobanks for further translational usage.
Authors
- Xuexin Yao
- Ranlin Yan
- Yingyan Yu (ORCID: https://orcid.org/0000-0002-3585-3252)
- Hengjun Gao (ORCID: https://orcid.org/0000-0001-8690-1632)
- Wingyan Kwan
- Zisis Kozlakidis (ORCID: https://orcid.org/0000-0002-3836-7209)
- Lu Zang (ORCID: https://orcid.org/0000-0002-0785-2033)
- Io Hong Cheong (ORCID: https://orcid.org/0000-0002-8573-7516)
- Zhenggang Zhu (ORCID: https://orcid.org/0000-0003-4769-5463)
- Chen Li (ORCID: https://orcid.org/0000-0003-3556-2719)
- Yutong Du (ORCID: https://orcid.org/0000-0001-7210-4675)
- Qi Yao (ORCID: https://orcid.org/0000-0002-1332-7323)
- Ruixin Yang (ORCID: https://orcid.org/0000-0002-6240-3089)
- Xiaoyan Zhang (ORCID: https://orcid.org/0009-0006-4262-2977)
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Shanghai Zhangjiang Laboratory (CN)
- Shanghai Institute of Hematology (CN)
- Centre international de recherche sur le cancer (FR)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1186/s12967-024-05512-0
- Citations
- 15
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 4.24
Funders
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality
- Shanghai Jiao Tong University
- School of Medicine, Shanghai Jiao Tong University