The Effect of Severe Coronary Calcification on Diagnostic Performance of Computed Tomography-Derived Fractional Flow Reserve Analyses in People with Coronary Artery Disease
Our results showed poor diagnostic accuracy of CCTA and cFFR in determining significant ischemia-related lesions in participants with high CAC scores when compared to ICA. Based on our results and study limitations we cannot exclude cFFR as a method for determining significant stenoses in people with high CAC. A key issue is accurate and detailed lumen segmentation based on good-quality CCTA images.
Authors
- Slavica Kovačić (ORCID: https://orcid.org/0000-0002-7419-224X)
- Tomislav Jakljević (ORCID: https://orcid.org/0000-0002-3692-0111)
- Tin Nadarević (ORCID: https://orcid.org/0000-0002-1174-5281)
- Nina Bartolović (ORCID: https://orcid.org/0000-0003-1402-8904)
- Iva Žuža (ORCID: https://orcid.org/0000-0002-5542-0091)
Institutions
- University Hospital Centre Zagreb (HR)
- University of Rijeka (HR)
Publication Details
- Journal
- Diagnostics
- Published
- 2024-08-10
- DOI
- https://doi.org/10.3390/diagnostics14161738
- Citations
- 1
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.40