Effects of semaglutide on gut microbiota, cognitive function and inflammation in obese mice
For the first time semaglutide displayed different regulatory effects on HFD-induced gut microbiota dysbiosis. Semaglutide could regulate the structure and composition of gut microbiota associated with cognitive function and inflammation. Thus, affecting gut microbiota might be a potential mechanism of semaglutide in attenuating cognitive function and inflammation.
Authors
- Jingzhen Liu (ORCID: https://orcid.org/0000-0002-4212-5958)
- Jing Feng (ORCID: https://orcid.org/0000-0001-5997-828X)
- Zhenjie Teng
- Shuchun Chen (ORCID: https://orcid.org/0000-0002-7747-3901)
- Yang Yu (ORCID: https://orcid.org/0000-0001-6584-4050)
Institutions
- Hebei Medical University (CN)
- Hebei General Hospital (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2024-08-12
- DOI
- https://doi.org/10.7717/peerj.17891
- Citations
- 37
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 8.65