Modifying Factors of the Incidence of Type 1 Diabetes Mellitus in Children under 18 Years of Age in Northern Spain in the Last 3 Decades

Introduction: Type 1 Diabetes Mellitus is a chronic disease of autoimmune etiology that is highly prevalent in childhood. In the last decade, the possibility of the influence of the Bacillus Calmette-Guérin vaccine, different autoimmune diseases, modification of the immune response, and COVID19 itself of a simple population change due to immigration. Objectives: The objective of this work is to study the incidence of Type 1 Diabetes Mellitus in a cohort of children from Euskadi, north of Spain in the last 15 years. Methods: For the epidemiological study in Euskadi, a comparison of accumulated incidences between vaccinated and unvaccinated population groups was made. Results: The results of our study were not conclusive, but we believe that it is necessary to continue with long-term studies to eliminate bias.