Targeted elimination of <i>Fusobacterium nucleatum</i> alleviates periodontitis
FP-100 effectively eliminates <i>F.</i> <i>nucleatum</i> from oral microbiota and significantly reduces bone loss in a mouse periodontitis model, demonstrating its potential as a targeted therapeutic agent for periodontal disease.
Authors
- Özge Ünlü (ORCID: https://orcid.org/0000-0002-5411-5925)
- Lujia Cen (ORCID: https://orcid.org/0000-0001-5982-1290)
- Wenyuan Shi (ORCID: https://orcid.org/0000-0003-2435-9256)
- Alpdoğan Kantarcı (ORCID: https://orcid.org/0000-0002-2679-9100)
- Nil Yakar (ORCID: https://orcid.org/0000-0002-0568-0928)
- Hatice Hastürk (ORCID: https://orcid.org/0000-0002-4395-3958)
- Tsute Chen (ORCID: https://orcid.org/0000-0001-6689-317X)
- Xuesong He (ORCID: https://orcid.org/0000-0002-3333-9188)
Institutions
- Harvard University (US)
- Ege University (TR)
- Atlas Üniversitesi
- Istanbul Arel University (TR)
Publication Details
- Journal
- Journal of Oral Microbiology
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1080/20002297.2024.2388900
- Citations
- 13
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 5.21
Funders
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
- National Institutes of Health
- National Institute of Dental and Craniofacial Research