Comparison of clinical characteristics and surgical outcomes in non‐vasectomized epididymal obstructive azoospermia patients with or without concurrent vas‐deferens obstruction

Our study identifies a noticeable occurrence of concurrent vas-deferens obstruction in non-vasectomized epididymal obstructive azoospermia patients, with approximately one-third of the cases (34.22%) exhibiting vas-deferens obstruction during surgical interventions. Notably, a small fraction (6.67%) of these individuals chose not to proceed with any microsurgical vasoepididymostomy, even on one side, due to the extensive length of the obstruction. Through logistic analysis, we have demonstrated that "the history of epididymitis" is a critical predictive factor for the presence of vas-deferens obstruction, underscoring its significance in preoperative evaluations. Furthermore, our research confirms that microsurgical vasoepididymostomy is still an effective treatment for epididymal obstructive azoospermia patients with concurrent short-segment vas-deferens obstruction, achieving significant patency and favorable pregnancy rates compared to those patients without vas-deferens obstruction. These insights are pivotal for enhancing surgical strategies and improving fertility outcomes in this patient cohort.

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Publication Details

Journal
Andrology
Published
2024-08-12
DOI
https://doi.org/10.1111/andr.13734
Primary Topic
Urologic and reproductive health conditions
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparison of clinical characteristics and surgical outcomes in non‐vasectomized epididymal obstructive azoospermia patients with or without concurrent vas‐deferens obstruction

Hui-Liang Zhou, Maoyuan Wang, Peng Yang, Yi-Lang Ding et al.
Andrology
Urologic and reproductive health conditions
article

Comparison of clinical characteristics and surgical outcomes in non‐vasectomized epididymal obstructive azoospermia patients with or without concurrent vas‐deferens obstruction

Hui-Liang Zhou, Maoyuan Wang, Peng Yang, Yi-Lang Ding, Xi Chen, Shan Zhou, Song-Xi Tang, Hong Xiao, Qiang Chen, Hai-Lin Huang
article en

Abstract

Our study identifies a noticeable occurrence of concurrent vas-deferens obstruction in non-vasectomized epididymal obstructive azoospermia patients, with approximately one-third of the cases (34.22%) exhibiting vas-deferens obstruction during surgical interventions. Notably, a small fraction (6.67%) of these individuals chose not to proceed with any microsurgical vasoepididymostomy, even on one side, due to the extensive length of the obstruction. Through logistic analysis, we have demonstrated that "the history of epididymitis" is a critical predictive factor for the presence of vas-deferens obstruction, underscoring its significance in preoperative evaluations. Furthermore, our research confirms that microsurgical vasoepididymostomy is still an effective treatment for epididymal obstructive azoospermia patients with concurrent short-segment vas-deferens obstruction, achieving significant patency and favorable pregnancy rates compared to those patients without vas-deferens obstruction. These insights are pivotal for enhancing surgical strategies and improving fertility outcomes in this patient cohort.

AndrologyVol. 13(4)
Fujian Medical University (CN), First Affiliated Hospital of Fujian Medical University (CN)
Natural Science Foundation of Fujian Province
Good health and well-being
Openalex Percentile: Top 76%
Urologic and reproductive health conditions
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