Brain amyloid load, subjective memory complaints, and cognitive trajectories in older individuals at risk for dementia
Amyloid accumulation may affect objective but not necessarily subjective cognition from a very early at-risk stage, although substantial decline likely requires >2 years to occur.
Authors
- Alina Solomon
- Gazi Saadmaan (ORCID: https://orcid.org/0000-0002-0925-7609)
- Anna Matton (ORCID: https://orcid.org/0000-0002-7819-0495)
- Tiia Ngandu (ORCID: https://orcid.org/0000-0002-3698-2021)
- Nina Kemppainen (ORCID: https://orcid.org/0000-0002-8988-5858)
- Gayle Wittenberg (ORCID: https://orcid.org/0009-0004-4299-5138)
- Francesca Mangialasche (ORCID: https://orcid.org/0000-0002-2686-3926)
- Juha O. Rinne (ORCID: https://orcid.org/0000-0001-6369-0764)
- Miia Kivipelto (ORCID: https://orcid.org/0009-0001-1069-1787)
- Anette Hall
Institutions
- Karolinska University Hospital (SE)
- University of Turku (FI)
- University of Eastern Finland (FI)
- Turku University Hospital (FI)
- Karolinska Institutet (SE)
- Finnish Institute for Health and Welfare (FI)
- Turku PET Centre (FI)
- Janssen (United States) (US)
- Imperial College London (GB)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1111/ene.16436
- Citations
- 1
- Primary Topic
- Cognitive Functions and Memory
- Type
- article
- Field-Weighted Citation Impact
- 0.51
Funders
- EU Joint Programme – Neurodegenerative Disease Research
- Kela
- Academy of Finland
- Juho Vainion Säätiö
- Karolinska Institutet
- Knut och Alice Wallenbergs Stiftelse
- Vetenskapsrådet
- NordForsk
- Sigrid Juséliuksen Säätiö
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd
- Alzheimerfonden
- European Research Council
- Center for Innovative Medicine