Novel one-pot synthesis of nitrogen-containing derivatives via C-N bond formation and C-O bond cleavage

Ortho-aminophenols are significant organic compounds known for their versatility and wide-ranging applications in materials science, synthesis, pharmaceuticals, agriculture, and industry. In this work, we present novel synthetic methods that utilize readily available and cost-effective materials, namely catechol, Cd(NO3)2 as a catalyst, and H2O/EtOH solvent. These proposed synthesis methods involve mild, one-pot reactions that facilitate the formation of both C-N and cleavage of C-O bond. This approach leads to the production of various nitrogen-containing derivatives with remarkably high yields and efficiency.