An Analysis of the Biocompatibility, Cytotoxicity, and Bone Conductivity of Polycaprolactone: An In Vivo Study
The findings demonstrate that PCL scaffolds produced through additive manufacturing are biocompatible, non-cytotoxic, and bioresorbable, promoting osteoconduction without adverse effects on major organs. Hence, PCL is confirmed as a suitable biomaterial for further studies in tissue engineering and regenerative medicine.
Authors
- Alexandre Weber (ORCID: https://orcid.org/0000-0002-0733-9475)
- Wâneza Dias Borges Hirsch (ORCID: https://orcid.org/0000-0003-2793-7218)
- Adriana Etges (ORCID: https://orcid.org/0000-0002-6066-869X)
- Paulo Inforçatti Neto (ORCID: https://orcid.org/0000-0001-8044-6018)
- Cláiton Heitz
- Frederico David Alencar de Sena Pereira
- Janaine Ferri
Institutions
- Universidade Federal de Pelotas (BR)
- Universidade Federal de Santa Maria (BR)
- Centro de Tecnologia da Informação Renato Archer (BR)
- Pontifícia Universidade Católica do Rio Grande do Sul (BR)
Publication Details
- Journal
- Polymers
- Published
- 2024-08-10
- DOI
- https://doi.org/10.3390/polym16162271
- Citations
- 11
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 2.03