A Novel Radial Basis and Sigmoid Neural Network Combination to Solve the Human Immunodeficiency Virus System in Cancer Patients

The purpose of this work is to design a novel process based on the deep neural network (DNN) process to solve the dynamical human immunodeficiency virus (HIV-1) infection system in cancer patients (HIV-1-ISCP). The dual hidden layer neural network structure using the combination of a radial basis and sigmoid function with twenty and forty neurons is presented for the solution of the nonlinear HIV-1-ISCP. The mathematical form of the model is divided into three classes named cancer population cells (T), healthy cells (H), and infected HIV (I) cells. The validity of the designed novel scheme is proven through the comparison of the results. The optimization is performed using a competent scale conjugate gradient procedure, the correctness of the proposed numerical approach is observed through the reference results, and negligible values of the absolute error are around 10−3 to 10−4. The database numerical solutions are achieved from the Runge–Kutta numerical scheme, and are used further to reduce the mean square error by taking 72% of the data for training, while 14% of the data is taken for testing and substantiations. To authenticate the credibility of this novel procedure, graphical plots using different performances are derived.

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Publication Details

Journal
Mathematics
Published
2024-08-12
DOI
https://doi.org/10.3390/math12162490
Citations
29
Primary Topic
Immunotherapy and Immune Responses
Type
article
Field-Weighted Citation Impact
6.97
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article

A Novel Radial Basis and Sigmoid Neural Network Combination to Solve the Human Immunodeficiency Virus System in Cancer Patients

Zulqurnain Sabir, S. Dirani, Sara Bou Saleh, Adnène Arbi et al.
29 citations
Mathematics
Immunotherapy and Immune Responses
6.97
article

A Novel Radial Basis and Sigmoid Neural Network Combination to Solve the Human Immunodeficiency Virus System in Cancer Patients

Zulqurnain Sabir, S. Dirani, Sara Bou Saleh, Adnène Arbi, Mohamad Khaled Mabsout
article en
29 citations

Abstract

The purpose of this work is to design a novel process based on the deep neural network (DNN) process to solve the dynamical human immunodeficiency virus (HIV-1) infection system in cancer patients (HIV-1-ISCP). The dual hidden layer neural network structure using the combination of a radial basis and sigmoid function with twenty and forty neurons is presented for the solution of the nonlinear HIV-1-ISCP. The mathematical form of the model is divided into three classes named cancer population cells (T), healthy cells (H), and infected HIV (I) cells. The validity of the designed novel scheme is proven through the comparison of the results. The optimization is performed using a competent scale conjugate gradient procedure, the correctness of the proposed numerical approach is observed through the reference results, and negligible values of the absolute error are around 10−3 to 10−4. The database numerical solutions are achieved from the Runge–Kutta numerical scheme, and are used further to reduce the mean square error by taking 72% of the data for training, while 14% of the data is taken for testing and substantiations. To authenticate the credibility of this novel procedure, graphical plots using different performances are derived.

MathematicsVol. 12(16)
University of Carthage (TN), Tunisia Polytechnic School (TN), Lebanese American University (LB)
Good health and well-being
Openalex Percentile: Top 2%
Immunotherapy and Immune Responses
6.97
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A Novel Radial Basis and Sigmoid Neural Network Combination to Solve the Human Immunodeficiency Virus System in Cancer Patients — Zulqurnain Sabir, S. Dirani, et al. · Mathematics (2024) | TGRS Research Map | TGRS