Diagnostic Performance of Renal Contrast Excretion on Early-Phase CT Myelography in Spontaneous Intracranial Hypotension
We found a statistically significant positive association between RCE and SIH diagnosis during early-phase CTM; however, clinically useful thresholds based on cutoff values for renal HU resulted in poor sensitivities or specificities, with substantial false-positives or false-negatives, respectively. Thus, while we confirmed statistically significant differences in RCE in the ≤30-minute period, in keeping with prior investigations of more delayed time periods, overlap in renal attenuation values prevented the development of clinically useful threshold values for discriminating SIH+ from SIH- patients.
Authors
- Derek S. Young (ORCID: https://orcid.org/0000-0002-3048-3803)
- Michael D. Malinzak (ORCID: https://orcid.org/0000-0002-6007-6520)
- Alaattin Erkanli
- Jay Willhite (ORCID: https://orcid.org/0000-0002-6501-2171)
- Samantha Morrison (ORCID: https://orcid.org/0000-0003-0787-8505)
- Timothy J. Amrhein (ORCID: https://orcid.org/0000-0002-9354-9486)
- Jacob T. Gibby
- Linda Gray (ORCID: https://orcid.org/0000-0001-5947-9552)
- Peter George Kranz (ORCID: https://orcid.org/0000-0001-5410-7135)
Institutions
- Duke University (US)
- Duke University Hospital (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2024-08-12
- DOI
- https://doi.org/10.3174/ajnr.a8435
- Primary Topic
- Neurosurgical Procedures and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Center for Advancing Translational Sciences