Age and Functional Outcomes in Patients With Large Ischemic Stroke Receiving Endovascular Thrombectomy

In this cohort study of patients with acute ischemic stroke and large infarct, age was associated with functional outcomes. Patients older than 80 years had poor prognosis with high mortality but with sizeable differences depending on additional baseline and treatment characteristics. While it does not seem justified to apply a fixed upper age limit for endovascular thrombectomy, these results could assist clinicians in making informed treatment decisions in older patients with large ischemic stroke.

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Publication Details

Journal
JAMA Network Open
Published
2024-08-12
DOI
https://doi.org/10.1001/jamanetworkopen.2024.26007
Citations
34
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
13.15
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article

Age and Functional Outcomes in Patients With Large Ischemic Stroke Receiving Endovascular Thrombectomy

Franziska Dorn, Tobias Djamsched Faizy, Sven Poli, Eberhard Siebert et al.
34 citations
JAMA Network Open
Acute Ischemic Stroke Management
13.15
article

Age and Functional Outcomes in Patients With Large Ischemic Stroke Receiving Endovascular Thrombectomy

Franziska Dorn, Tobias Djamsched Faizy, Sven Poli, Eberhard Siebert, Joachim Röther, Götz Thomalla, Jan Liman, Gabor C. Petzold, Gerhard F. Hamann, Christian Heitkamp, Christian H. Nolte, Helge C. Kniep, Maximilian Schell, Arno Reich, Marielle Ernst, Georg Böhner, Steffen Tiedt, Sarah Zweynert, Klaus Gröschel, Jan Borggrefe, Fabian Flottmann, Lukas Meyer, Lars Kellert, Florian Stögbauer, Michael Braun, Laurens Winkelmeier, Fee Christiane Keil, Gabriel Broocks, Timo Uphaus, Tobias Boeckh‐Behrens, Christoph Trumm, Anna Allegiani, Alexander Ludolf, Christian Gerloff, Silke Wunderlich, Peter D. Schellinger, Ulrike Ernemann, Ruben Mühl‐Benninghaus, Christoffer Kraemer, Omid Nikoubashman, Martina Petersen, Alexander Heitkamp, Christian Riedel, Jens Fiehler, Albrecht Bormann, Jan Hendrik Schäfer, Ludovic Holtz, Jörg Berrouschot, Jörg Hattingen, Bernd Eckert, Karl‐Heinz Henn
article en
34 citations

Abstract

In this cohort study of patients with acute ischemic stroke and large infarct, age was associated with functional outcomes. Patients older than 80 years had poor prognosis with high mortality but with sizeable differences depending on additional baseline and treatment characteristics. While it does not seem justified to apply a fixed upper age limit for endovascular thrombectomy, these results could assist clinicians in making informed treatment decisions in older patients with large ischemic stroke.

JAMA Network OpenVol. 7(8)
Universität Hamburg (DE), MSH Medical School Hamburg – University of Applied Sciences and Medical University (DE), Helios Hospital Schwerin (DE), University Hospital Münster (DE), University Medical Center Hamburg-Eppendorf (DE)
Good health and well-being
Openalex Percentile: Top 1%
Acute Ischemic Stroke Management
13.15
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