TTI-101 targets STAT3/c-Myc signaling pathway to suppress cervical cancer progression: an integrated experimental and computational analysis

TTI-101 exhibited anticancer effects by targeting the STAT3/c-Myc signaling pathway, inducing cell cycle arrest, and promoting apoptosis in CC cells. These findings provide valuable insights into the development of novel therapeutic strategies for cervical cancer. Further investigation is warranted to validate the clinical application of TTI-101.

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Publication Details

Journal
Cancer Cell International
Published
2024-08-12
DOI
https://doi.org/10.1186/s12935-024-03463-6
Citations
5
Primary Topic
Cytokine Signaling Pathways and Interactions
Type
article
Field-Weighted Citation Impact
1.41
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article

TTI-101 targets STAT3/c-Myc signaling pathway to suppress cervical cancer progression: an integrated experimental and computational analysis

Yuyan Dong, Yi Li
5 citations
Cancer Cell International
Cytokine Signaling Pathways and Interactions
1.41
article

TTI-101 targets STAT3/c-Myc signaling pathway to suppress cervical cancer progression: an integrated experimental and computational analysis

Yuyan Dong, Yi Li
article en
5 citations

Abstract

TTI-101 exhibited anticancer effects by targeting the STAT3/c-Myc signaling pathway, inducing cell cycle arrest, and promoting apoptosis in CC cells. These findings provide valuable insights into the development of novel therapeutic strategies for cervical cancer. Further investigation is warranted to validate the clinical application of TTI-101.

Cancer Cell InternationalVol. 24(1)
Shandong University (CN), Shandong Provincial Hospital (CN), Shandong Maternal and Child Health Hospital (CN)
Good health and well-being
Openalex Percentile: Top 16%
Cytokine Signaling Pathways and Interactions
1.41
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TTI-101 targets STAT3/c-Myc signaling pathway to suppress cervical cancer progression: an integrated experimental and computational analysis — Yuyan Dong, Yi Li · Cancer Cell International (2024) | TGRS Research Map | TGRS