Development, validation and use of custom software for the analysis of pain trajectories

In chronic musculoskeletal conditions, the prognosis tends to be more informative than the diagnosis for the future course of the disease. Many studies have identified clusters of patients who seemingly share similar pain trajectories. In a dataset of low back pain (LBP) patients, pain trajectories have been identified, and distinct trajectory types have been defined, making it possible to create pattern recognition software that can classify patients into respective pain trajectories reflecting their condition. It has been suggested that the classification of pain trajectories may create clinically meaningful subgroups of patients in an otherwise heterogeneous population of patients with LBP. A software tool was created that combined the ability to recognise the pain trajectory of patients with a system that could create subgroups of patients based on their characteristics. This tool is primarily meant for researchers to analyse trends in large heterogeneous datasets without large losses of data. Prospective analysis of pain trajectories is not directly helpful for clinicians. However, the tool might aid in the identification of patient characteristics which have predictive capabilities of the most likely trajectory a patient might experience in the future. This will help clinicians to tailor their advice and treatment for a specific patient.

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Publication Details

Journal
Scientific Reports
Published
2024-08-12
DOI
https://doi.org/10.1038/s41598-024-69574-2
Primary Topic
Musculoskeletal pain and rehabilitation
Type
article
Field-Weighted Citation Impact
0.00
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article

Development, validation and use of custom software for the analysis of pain trajectories

Peter W. McCarthy, Annemarie de Zoete, Hasan Al-Madfai, Alice Kongsted et al.
Scientific Reports
Musculoskeletal pain and rehabilitation
article

Development, validation and use of custom software for the analysis of pain trajectories

Peter W. McCarthy, Annemarie de Zoete, Hasan Al-Madfai, Alice Kongsted, Sidney M. Rubinstein, M. R. van Ittersum
article en

Abstract

In chronic musculoskeletal conditions, the prognosis tends to be more informative than the diagnosis for the future course of the disease. Many studies have identified clusters of patients who seemingly share similar pain trajectories. In a dataset of low back pain (LBP) patients, pain trajectories have been identified, and distinct trajectory types have been defined, making it possible to create pattern recognition software that can classify patients into respective pain trajectories reflecting their condition. It has been suggested that the classification of pain trajectories may create clinically meaningful subgroups of patients in an otherwise heterogeneous population of patients with LBP. A software tool was created that combined the ability to recognise the pain trajectory of patients with a system that could create subgroups of patients based on their characteristics. This tool is primarily meant for researchers to analyse trends in large heterogeneous datasets without large losses of data. Prospective analysis of pain trajectories is not directly helpful for clinicians. However, the tool might aid in the identification of patient characteristics which have predictive capabilities of the most likely trajectory a patient might experience in the future. This will help clinicians to tailor their advice and treatment for a specific patient.

Scientific ReportsVol. 14(1)
University of South Wales (GB), Durban University of Technology (ZA), University of Southern Denmark (DK), Erasmus MC (NL), Geneeskundige en Gezondheidsdienst (NL), Vrije Universiteit Amsterdam (NL), AGCO (Netherlands) (NL)
Openalex Percentile: Top 87%
Musculoskeletal pain and rehabilitation
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