Resveratrol attenuates non-steroidal anti-inflammatory drug-induced intestinal injury in rats in a high-altitude hypoxic environment by modulating the TLR4/NFκB/IκB pathway and gut microbiota composition
Resveratrol can attenuate intestinal damage caused by the administration of NSAIDs at high altitude in hypoxic environments by modulating the TLR4/NF-κB/IκB signaling pathway and gut microbiota composition.
Authors
- Feng Gao (ORCID: https://orcid.org/0000-0002-3320-5702)
- Yingying Xing (ORCID: https://orcid.org/0000-0001-5566-3096)
- Wenhui Shi (ORCID: https://orcid.org/0000-0002-4338-4046)
- Weidong Liu (ORCID: https://orcid.org/0000-0003-3320-3958)
- Shenglong Xue (ORCID: https://orcid.org/0009-0009-0650-8300)
- Kailibinuer Nuermaimaiti
- Kudelaiti Abdukelimu
- Ailifeire Tuerxuntayi
- Najimangu Remutula
- Paziliya Abulaiti
- Zhuoshuyi Liu
- Tian Shi
Institutions
- Xinjiang Medical University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Urumqi General Hospital of PLA (CN)
- Xinjiang University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1371/journal.pone.0305233
- Citations
- 10
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 5.50
Funders
- Natural Science Foundation of Xinjiang Province
- National Natural Science Foundation of China
- Natural Science Foundation of Xinjiang