Causality between migraine and cardiovascular disease: a bidirectional Mendelian randomization study
We found a potential protective effect of migraine on coronary artery disease and ischemic stroke and a potential protective effect of coronary atherosclerosis and myocardial infarction on migraine. We emphasised epidemiological and genetic differences and the need for long-term safety monitoring of migraine medications and future research to improve cardiovascular outcomes in migraine patients.
Authors
- Xinyan Zhou (ORCID: https://orcid.org/0000-0002-3887-8121)
- Chengde Liao (ORCID: https://orcid.org/0000-0002-8891-7555)
- Guangrong Zheng (ORCID: https://orcid.org/0000-0002-8106-6663)
- Guochen Li (ORCID: https://orcid.org/0009-0009-1106-4345)
- Na Tan (ORCID: https://orcid.org/0000-0002-9177-5666)
- Tengfei Ke (ORCID: https://orcid.org/0009-0002-7513-4997)
- Bin Liu (ORCID: https://orcid.org/0000-0002-6219-3093)
- Xiaolan Du (ORCID: https://orcid.org/0000-0001-5979-7999)
- Xirui Duan
- Mei Chun Zhu
Institutions
- Kunming Medical University (CN)
- Yan'an Hospital Affiliated To Kunming Medical University (CN)
- Third People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1186/s10194-024-01836-w
- Citations
- 6
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.31
Funders
- National Natural Science Foundation of China
- Yunnan Provincial Department of Education