Serum Levels of Plasminogen Activator Inhibitor-1 in Patients with Parkinson’s Disease
This is the first comprehensive analysis of serum PAI-1 levels in patients with PD. The distribution of PAI-1 in PD appears to be complex. The study results implicate that the paradoxical effects of tissue plasminogen activator on the brain parenchyma can be important in the pathophysiology of PD. Future studies are needed to elucidate the role of fibrinolytic system components in PD.
Authors
- Azra Meryem Tanrikulu (ORCID: https://orcid.org/0000-0002-1671-0416)
- Betül Özdilek (ORCID: https://orcid.org/0000-0003-1608-9882)
- Mehmet Ağırbaşlı (ORCID: https://orcid.org/0000-0002-4873-4391)
Institutions
- Ministry of Health (TR)
- Istanbul Medeniyet University (TR)
Publication Details
- Journal
- Medical Principles and Practice
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1159/000540854
- Citations
- 2
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.74