Mechanisms of QingRe HuoXue Formula in atherosclerosis Treatment: An integrated approach using Bioinformatics, Machine Learning, and experimental validation
We revealed the inflammatory and immune pathways underlying QRHXF treatment for AS, and verified through transcriptome sequencing and experiments that QRHXF can promote the expression of COL1A1, thereby increasing the stability of AS plaques.
Authors
- Zhichao Lin (ORCID: https://orcid.org/0000-0002-7354-8435)
- Chuanjin Luo (ORCID: https://orcid.org/0000-0002-1691-104X)
- Qing Miao (ORCID: https://orcid.org/0000-0002-5975-3010)
- Peijian Liu
- Qingmin Chu (ORCID: https://orcid.org/0000-0002-1144-5211)
- Wei Wu (ORCID: https://orcid.org/0009-0005-8873-9380)
- Yuling Zhang (ORCID: https://orcid.org/0000-0002-1404-6101)
- Kunsheng Wu
- Guiting Zhou (ORCID: https://orcid.org/0000-0001-7841-3460)
- Rui Peng (ORCID: https://orcid.org/0000-0002-1654-0402)
- Shushu Wang
- Liwen Lin (ORCID: https://orcid.org/0009-0007-0824-2310)
- Kachun Lu
- Wanwen Kong
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1016/j.intimp.2024.112890
- Citations
- 6
- Primary Topic
- Traditional Chinese Medicine Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.30