A novel multisite model to facilitate hepatitis C virus elimination in people experiencing homelessness

In people experiencing homeless, we found a high prevalence of HCV, alcohol, and substance misuse including overdoses and mental health issues. Despite this, an integrated and decentralised service resulted in excellent linkage to care with high SVR12 rates. Even in this complex cohort with multiple comorbidities, SVR12 was associated with significant improvements in both generic and liver specific HRQoL. This was all achieved at modest costs in a community setting. Such models of care are feasible, easy to replicate, and essential if we are to achieve HCV elimination.

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Publication Details

Journal
JHEP Reports
Published
2024-08-12
DOI
https://doi.org/10.1016/j.jhepr.2024.101183
Citations
3
Primary Topic
Homelessness and Social Issues
Type
article
Field-Weighted Citation Impact
2.55

Funders

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article

A novel multisite model to facilitate hepatitis C virus elimination in people experiencing homelessness

Emma Gray, Rona McGeer, Vikki Charles, Anna‐Marie Jones et al.
3 citations
JHEP Reports
Homelessness and Social Issues
2.55
article

A novel multisite model to facilitate hepatitis C virus elimination in people experiencing homelessness

Emma Gray, Rona McGeer, Vikki Charles, Anna‐Marie Jones, Sumita Verma, Lidia Salvaggio, Adele Mourad, Margaret O’Sullivan, Natasha Sanderson, Thomas D. Bird, Heather Gage
article en
3 citations

Abstract

In people experiencing homeless, we found a high prevalence of HCV, alcohol, and substance misuse including overdoses and mental health issues. Despite this, an integrated and decentralised service resulted in excellent linkage to care with high SVR12 rates. Even in this complex cohort with multiple comorbidities, SVR12 was associated with significant improvements in both generic and liver specific HRQoL. This was all achieved at modest costs in a community setting. Such models of care are feasible, easy to replicate, and essential if we are to achieve HCV elimination.

JHEP ReportsVol. 6(11)
Brighton and Sussex Medical School (GB), Sussex Partnership NHS Foundation Trust (GB), University of Surrey (GB), Royal Surrey NHS Foundation Trust (GB), University Hospitals Sussex NHS Foundation Trust (GB)
Gilead Sciences
Reduced inequalities
Openalex Percentile: Top 10%
Homelessness and Social Issues
2.55
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A novel multisite model to facilitate hepatitis C virus elimination in people experiencing homelessness — Emma Gray, Rona McGeer, et al. · JHEP Reports (2024) | TGRS Research Map | TGRS