Antibiotic Resistance Profiles Of Bacterial Isolates From Patients With Pneumonia In Arish General Hospital, North Sinai: Molecular Identification Of The Most Resistant Strain

A significant public health concern, bacterial pneumonia increases illness and mortality worldwide and presents significant medical and financial difficulties. Furthermore, the increase in antibiotic resistance, particularly in Gram-negative bacteria, complicates therapy and affects patient outcomes. Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii are common resistant bacteria that cause pneumonia. Our investigation aimed to isolate and describe pathogenic bacteria from sputum samples, evaluating their antibiotic susceptibility profiles and identifying the most resistant strain by molecular methods. According to our research, a female patient at Arish General Hospital in Governorate North Sinai had a sputum sample that was used to successfully isolate a Gram-negative bacterium known as Klebsiella pneumoniae. The importance of this study is in its ability to shed light on the incidence of pathogenic bacteria that are resistant to antibiotics in patients with pneumonia. It is important to act on antibiotic resistance in clinical settings because our isolated strain is resistant to twelve different antibiotics.