Association of hTERT expression, Her2Neu, estrogen receptors, progesterone receptors, with telomere length before and at the end of treatment in breast cancer patients
Positive hTERT immunostaining cases were associated with poor prognostic factors, such as Her2-Neu overexpression and post-treatment telomere shortening. In the future, hTERT immunostaining could be used to select patients for therapies with antagonistic effects on hTERT, as well as in the selection of more appropriate chemotherapy regimens for patients who express it.
Authors
- Blanca Murillo-Ortíz (ORCID: https://orcid.org/0000-0003-4775-2755)
- Mario Murguía‐Pérez (ORCID: https://orcid.org/0000-0003-4260-389X)
- Saulo Mendoza-Ramírez
- Sandra Martı́nez-Garza (ORCID: https://orcid.org/0000-0002-2153-6619)
- Eduardo Agustín-Godínez
- Kenia García-Corrales
- Marcos Javier Romero-Vázquez (ORCID: https://orcid.org/0009-0000-2520-602X)
- Andrea Escareño-Gómez
- Daniela Guadalupe Silva-Guerrero
Institutions
- Mexican Social Security Institute (MX)
- Hospital General de México (MX)
- Hospital General De Zona (MX)
- Hospital de Especialidades (MX)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2024-08-12
- DOI
- https://doi.org/10.3389/fmed.2024.1450147
- Citations
- 4
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 1.31