Prognostic value of four immune-related genes in lower-grade gliomas: a biomarker discovery study

Our study highlights the prognostic significance of the identified four DEIRGs (KLRC3, MR1, PDIA2, and RFXAP) in LGG patients. The predictive model and nomogram developed herein offer valuable tools for personalized treatment strategies in LGG. Future research should focus on further validating these findings and exploring the functional roles of these DEIRGs within the LGG tumor microenvironment.

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Publication Details

Journal
Frontiers in Genetics
Published
2024-08-12
DOI
https://doi.org/10.3389/fgene.2024.1403587
Citations
3
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.31
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article

Prognostic value of four immune-related genes in lower-grade gliomas: a biomarker discovery study

Jianxin Wu, Shuowen Wang, Zijun Wang, Zhuo Liu
3 citations
Frontiers in Genetics
Glioma Diagnosis and Treatment
1.31
article

Prognostic value of four immune-related genes in lower-grade gliomas: a biomarker discovery study

Jianxin Wu, Shuowen Wang, Zijun Wang, Zhuo Liu
article en
3 citations

Abstract

Our study highlights the prognostic significance of the identified four DEIRGs (KLRC3, MR1, PDIA2, and RFXAP) in LGG patients. The predictive model and nomogram developed herein offer valuable tools for personalized treatment strategies in LGG. Future research should focus on further validating these findings and exploring the functional roles of these DEIRGs within the LGG tumor microenvironment.

Frontiers in GeneticsVol. 15
Beijing Tongren Hospital (CN), Capital Medical University (CN), Capital Institute of Pediatrics (CN), Beijing Shijitan Hospital (CN)
Good health and well-being
Openalex Percentile: Top 19%
Glioma Diagnosis and Treatment
1.31
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