Generation of a mouse model of thyroid storm and preliminary investigation of the therapeutic effects of ghrelin
We established an animal model of TS that exhibits pathophysiological states similar to human TS with induction of serum IL-6 and other biomarkers by administration of T3 and LPS. The results suggest the potential effectiveness of ghrelin for TS in humans.
Authors
- Taka‐aki Matsuoka (ORCID: https://orcid.org/0000-0002-9952-9873)
- Hiroyuki Ariyasu (ORCID: https://orcid.org/0000-0002-9307-1275)
- Chiaki Kurimoto
- Asako Doi (ORCID: https://orcid.org/0000-0002-8993-0081)
- Hiroto Furuta (ORCID: https://orcid.org/0000-0003-1657-3519)
- Shuhei Morita (ORCID: https://orcid.org/0000-0002-4415-3805)
- Hiroshi Iwakura (ORCID: https://orcid.org/0000-0001-8033-0736)
- Takashi Akamizu (ORCID: https://orcid.org/0000-0003-4960-8271)
- Ken Takeshima
- Masahiro Nishi (ORCID: https://orcid.org/0000-0001-9644-4834)
- Yasushi Furukawa
Institutions
- Wakayama Medical University (JP)
- Kansai University of Nursing and Health Sciences (JP)
- Shizuoka General Hospital (JP)
- Kuma Hospital (JP)
Publication Details
- Journal
- BMC Endocrine Disorders
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1186/s12902-024-01680-8
- Citations
- 1
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.27
Funders
- Wakayama Medical University