BMP10 accelerated spinal astrocytic activation in neuropathic pain via ALK2/smad1/5/8 signaling
These findings indicate that the BMP10/ALK2/Smad1/5/8 axis plays a key role in pain hypersensitivity after peripheral nerve injury, which indicates its stimulative ability toward astrocytes.
Authors
- Xuejuan Zhang (ORCID: https://orcid.org/0000-0003-3330-3537)
- Bangjian Zhang
- Min Luo (ORCID: https://orcid.org/0000-0002-1506-0474)
- Yuehui Zhang (ORCID: https://orcid.org/0000-0001-5257-1671)
- Jiang Bian (ORCID: https://orcid.org/0000-0002-9034-4960)
- Yunyun Tian
- Li Yin (ORCID: https://orcid.org/0000-0003-0435-6656)
Institutions
- Zunyi Medical University (CN)
- First People’s Hospital of Zunyi (CN)
- Panzhihua Central Hospital (CN)
- Dali University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-12
- DOI
- https://doi.org/10.3389/fphar.2024.1426121
- Citations
- 4
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Department of Science and Technology of Sichuan Province