The HUNT lung-SNP model: genetic variants plus clinical variables improve lung cancer risk assessment over clinical models
The HUNT Lung-SNP model could have a clinical impact on LC screening and has the potential to replace the HUNT LCM as well as the NLST, NELSON and 2021 USPSTF criteria in a screening setting. However, the model should be further validated in other populations and evaluated in a prospective trial setting.
Authors
- Vincenzo Lagani (ORCID: https://orcid.org/0000-0002-6552-6076)
- Oluf Dimitri Røe (ORCID: https://orcid.org/0000-0002-4870-5822)
- Ioannis Fotopoulos (ORCID: https://orcid.org/0000-0002-1700-8362)
- Therese Haugdahl Nøst (ORCID: https://orcid.org/0000-0001-6805-3094)
- Ioannis Tsamardinos (ORCID: https://orcid.org/0000-0002-2492-959X)
- Olav Toai Duc Nguyen (ORCID: https://orcid.org/0009-0007-4939-5217)
- Maria Markaki (ORCID: https://orcid.org/0000-0001-5779-2078)
Institutions
- University of Crete (GR)
- Ilia State University (GE)
- Norwegian University of Science and Technology (NO)
- Aalborg University Hospital (DK)
- Levanger Hospital (NO)
- Science and Technology Park of Crete (GR)
- FORTH Institute of Applied and Computational Mathematics (GR)
- Artificial Intelligence in Medicine (Canada) (CA)
- King Abdullah University of Science and Technology (SA)
- UiT The Arctic University of Norway (NO)
- Aalborg University (DK)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2024-08-12
- DOI
- https://doi.org/10.1007/s00432-024-05909-w
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Norges Teknisk-Naturvitenskapelige Universitet
- Helse Midt-Norge
- Universitetet i Oslo
- Norges Forskningsråd
- St. Olavs Hospital Universitetssykehuset i Trondheim