Hydrolyzed conchiolin protein inhibits melanogenesis through PKA/CREB and MEK/ERK signalling pathways
These results suggest that HCP suppresses the melanogenesis signalling cascade by inhibiting the PKA/CREB, MEK/ERK signalling pathway and downregulating MITF and its downstream signalling pathways, resulting in decreased melanin synthesis. In summary, HCP is a potential anti-pigmentation agent with promising applications in cosmetics and pharmaceutical products.
Authors
- Anquan Yang (ORCID: https://orcid.org/0000-0001-8996-8605)
- Sisi Wang (ORCID: https://orcid.org/0000-0003-2566-4578)
- Yaqi Zhang (ORCID: https://orcid.org/0000-0002-3173-3843)
Institutions
- Sino Biological (China) (CN)
Publication Details
- Journal
- International Journal of Cosmetic Science
- Published
- 2024-08-11
- DOI
- https://doi.org/10.1111/ics.13012
- Citations
- 4
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 1.30