Dosimetric predictors of acute and late gastrointestinal toxicities in stereotactic online adaptive magnetic resonance-guided radiotherapy (SMART) for locally advanced pancreatic adenocarcinoma
For LAPC treated with SMART, the dose-volume threshold of V33Gy for duodenum and SB was associated with Gr2+ toxicities. These metrics can be utilized to guide future dose-volume constraints for patients undergoing upper abdominal SBRT.
Authors
- Alden D'Souza
- H.B. Stowe (ORCID: https://orcid.org/0000-0003-1331-5370)
- Lauren E. Henke (ORCID: https://orcid.org/0000-0003-2208-3241)
- John Ginn (ORCID: https://orcid.org/0000-0002-5694-9392)
- Pamela Samson (ORCID: https://orcid.org/0000-0003-2448-2123)
- B. Maraghechi (ORCID: https://orcid.org/0000-0002-3743-3956)
- Shahed N. Badiyan (ORCID: https://orcid.org/0000-0001-6243-526X)
- Joshua P. Schiff (ORCID: https://orcid.org/0000-0002-0661-4420)
- Kylie H. Kang (ORCID: https://orcid.org/0000-0002-4484-3689)
- Clifford G. Robinson (ORCID: https://orcid.org/0000-0002-1399-9904)
- Geoffrey D. Hugo (ORCID: https://orcid.org/0000-0002-4109-8177)
- Olga L. Green
- Hyun Kim (ORCID: https://orcid.org/0000-0003-4029-8764)
- Alex Price
Institutions
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Duke University (US)
- University of California, Irvine (US)
- Washington University in St. Louis (US)
- University Hospitals of Cleveland (US)
- Fred Hutch Cancer Center (US)
- Southwestern Medical Center (US)
- Duke Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2024-08-11
- DOI
- https://doi.org/10.1016/j.radonc.2024.110473
- Citations
- 3
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Sun Nuclear Corporation
- Varian Medical Systems