Species‐level, metagenomic and proteomic analysis of microbe‐immune interactions in severe asthma
This species-level integrated analysis reveals central, but distinct associations between potentially pathogenic bacteria and airways inflammation in severe asthma.
Authors
- Thomas Brown (ORCID: https://orcid.org/0000-0001-7336-4719)
- Emanuele Marchi (ORCID: https://orcid.org/0000-0003-1741-9353)
- Gillian E. Donachie (ORCID: https://orcid.org/0000-0002-8873-6455)
- Paul Klenerman (ORCID: https://orcid.org/0000-0003-4307-9161)
- Timothy Hinks (ORCID: https://orcid.org/0000-0003-0699-2373)
- Adnan Azim (ORCID: https://orcid.org/0000-0001-5960-1159)
- Maisha Jabeen (ORCID: https://orcid.org/0000-0002-1887-596X)
- Anoop Chauhan (ORCID: https://orcid.org/0000-0003-4044-6114)
- Clair Barber (ORCID: https://orcid.org/0000-0001-5335-5129)
- Laurie C.K. Lau (ORCID: https://orcid.org/0000-0002-5851-3867)
- Nicholas D. Sanderson (ORCID: https://orcid.org/0000-0001-6370-1961)
- Teresa L. Street (ORCID: https://orcid.org/0000-0001-8491-240X)
- Ian Pavord (ORCID: https://orcid.org/0000-0002-4288-5973)
- Peter Howarth (ORCID: https://orcid.org/0000-0003-0619-7927)
- Mariaenrica Tinè (ORCID: https://orcid.org/0000-0002-3094-5721)
Institutions
- University of Padua (IT)
- John Radcliffe Hospital (GB)
- National Institute for Health and Care Research (GB)
- University of Oxford (GB)
- Portsmouth Hospitals NHS Trust (GB)
- Medawar Building for Pathogen Research (GB)
- NIHR Southampton Respiratory Biomedical Research Unit (GB)
- University of Southampton (GB)
Publication Details
- Journal
- Allergy
- Published
- 2024-08-11
- DOI
- https://doi.org/10.1111/all.16269
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Pfizer
- AstraZeneca
- Sanofi
- Teva Pharmaceutical Industries
- Wellcome Trust
- UK Research and Innovation
- National Institute for Health and Care Research
- Department of Health and Social Care
- University of Oxford
- National Institute for Health Research Southampton Biomedical Research Centre
- Sanofi Genzyme
- Medical Research Council
- NIHR Oxford Biomedical Research Centre