The mitochondrial pyruvate carrier regulates adipose glucose partitioning in female mice
These findings highlight the greater capacity for mitochondrially driven triglyceride assembly in adipose from female versus male mice and expose a reliance upon MPC-gated metabolism for glucose partitioning in female adipose under conditions of dietary lipid restriction.
Authors
- Chris E. Shannon (ORCID: https://orcid.org/0000-0003-0240-0609)
- Marcel Fourcaudot
- Martina Wallace (ORCID: https://orcid.org/0000-0001-8272-5678)
- Leandro Ceotto Freitas‐Lima (ORCID: https://orcid.org/0000-0001-9550-6095)
- Luke Norton (ORCID: https://orcid.org/0000-0002-0231-5722)
- Iriscilla Ayala (ORCID: https://orcid.org/0000-0003-3374-9424)
- Edgar A. Hinostroza
- Terry M. Bakewell
- Mara Asmis
- Giovanna Romero
- Annie A. Smelter
Institutions
- University College Dublin (IE)
- The University of Texas at San Antonio Health Science Center (US)
- The University of Texas at San Antonio (US)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2024-08-11
- DOI
- https://doi.org/10.1016/j.molmet.2024.102005
- Citations
- 3
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.98
Funders
- Physiological Society
- European Commission
- National Institute of Diabetes and Digestive and Kidney Diseases
- H2020 Marie Skłodowska-Curie Actions
- Division of Diabetes, Endocrinology, and Metabolic Diseases