In mouse model of mixed granulocytic asthma with corticosteroid refractoriness, Bronchom mitigates airway hyperresponsiveness, inflammation and airway remodeling
We have demonstrated for the first time the robust pharmacological effects of an herbo-mineral medicine in an animal model of mixed granulocytic asthma induced by HDM and CFA. The outcomes suggest the potential utility of Bronchom in severe asthmatics with a mixed granulocytic phenotype.
Authors
- Rani Singh (ORCID: https://orcid.org/0000-0002-5819-4050)
- Monali Joshi
- Surjeet Singh (ORCID: https://orcid.org/0000-0002-4646-2089)
- Anurag Varshney (ORCID: https://orcid.org/0000-0001-8509-0882)
- Acharya Balkrishna (ORCID: https://orcid.org/0000-0003-4749-6317)
- Sandeep Sinha (ORCID: https://orcid.org/0000-0003-1326-3769)
- Abhishek Pandey
Institutions
- Jawaharlal Nehru University (IN)
- Patanjali Research Foundation (IN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-08-11
- DOI
- https://doi.org/10.1186/s10020-024-00888-7
- Citations
- 4
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.31