Total sulfur amino acid requirements are higher during late gestation compared with early gestation in healthy Canadian pregnancies in a repeated-measures trial
We directly measured TSAA requirements in healthy pregnant mothers, and our findings suggest that requirements are lower than current DRI recommendations of 20 and 25 mg⋅kg<sup>-1</sup>⋅d<sup>-1</sup>, as the EAR, and Recommended Dietary Allowance, respectively. Late gestation TSAA needs are significantly different and increased 35% compared with early gestation. Recommendations for TSAA intake need to be tailored for gestational stage. This clinical trial was registered at clinicaltrials.gov as NCT04326322.
Authors
- Glenda Courtney‐Martin (ORCID: https://orcid.org/0000-0001-6835-1366)
- Rajavel Elango (ORCID: https://orcid.org/0000-0002-9380-1725)
- Kerri Scherbinsky (ORCID: https://orcid.org/0000-0003-2311-808X)
- Betina Rasmussen (ORCID: https://orcid.org/0000-0001-6491-6470)
- Bingqing Li
- Dehan Kong (ORCID: https://orcid.org/0000-0003-3480-4915)
- Paul B. Pencharz
- Ronald O. Ball
Institutions
- University of British Columbia (CA)
- University of Alberta (CA)
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- BC Children's Hospital (CA)
Publication Details
- Journal
- American Journal of Clinical Nutrition
- Published
- 2024-08-10
- DOI
- https://doi.org/10.1016/j.ajcnut.2024.07.034
- Citations
- 3
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 3.33
Funders
- BC Children's Hospital
- Hospital for Sick Children
- Canadian Institutes of Health Research