Intracranial ependymomas in pediatric patients: patterns of care, disparities, and survival outcomes from the National Cancer Database
This comprehensive analysis of the NCDB provides valuable insights into the epidemiology, treatment patterns, and survival outcomes of intracranial ependymomas in pediatric patients. Higher tumor grade, infratentorial localization, and chemotherapy use was associated with worse OS, while larger tumor size correlated with lower mortality hazard. Disparities in care were identified, with uninsured patients experiencing prolonged LOS. These findings underscore the need for tailored treatment strategies based on patient and tumor characteristics and highlight the importance of addressing socioeconomic barriers to optimize outcomes for children with ependymomas.
Authors
- Peter Morgenstern (ORCID: https://orcid.org/0000-0002-2409-3614)
- Konstantinos D. Margetis (ORCID: https://orcid.org/0000-0002-3715-8093)
- Mert Karabacak (ORCID: https://orcid.org/0000-0002-9263-9893)
- Chi Hieu Le (ORCID: https://orcid.org/0000-0002-5168-2297)
- Pemla Jagtiani (ORCID: https://orcid.org/0000-0002-6075-0255)
- Zeynep Bahadir
Institutions
- Mount Sinai Health System (US)
- SUNY Downstate Health Sciences University (US)
- Cornell University (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- Journal of Neurosurgery Pediatrics
- Published
- 2024-08-10
- DOI
- https://doi.org/10.3171/2024.5.peds2480
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.88