Intracranial ependymomas in pediatric patients: patterns of care, disparities, and survival outcomes from the National Cancer Database

This comprehensive analysis of the NCDB provides valuable insights into the epidemiology, treatment patterns, and survival outcomes of intracranial ependymomas in pediatric patients. Higher tumor grade, infratentorial localization, and chemotherapy use was associated with worse OS, while larger tumor size correlated with lower mortality hazard. Disparities in care were identified, with uninsured patients experiencing prolonged LOS. These findings underscore the need for tailored treatment strategies based on patient and tumor characteristics and highlight the importance of addressing socioeconomic barriers to optimize outcomes for children with ependymomas.

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Publication Details

Journal
Journal of Neurosurgery Pediatrics
Published
2024-08-10
DOI
https://doi.org/10.3171/2024.5.peds2480
Citations
2
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.88
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article

Intracranial ependymomas in pediatric patients: patterns of care, disparities, and survival outcomes from the National Cancer Database

Peter Morgenstern, Konstantinos D. Margetis, Mert Karabacak, Chi Hieu Le et al.
2 citations
Journal of Neurosurgery Pediatrics
Glioma Diagnosis and Treatment
0.88
article

Intracranial ependymomas in pediatric patients: patterns of care, disparities, and survival outcomes from the National Cancer Database

Peter Morgenstern, Konstantinos D. Margetis, Mert Karabacak, Chi Hieu Le, Pemla Jagtiani, Zeynep Bahadir
article en
2 citations

Abstract

This comprehensive analysis of the NCDB provides valuable insights into the epidemiology, treatment patterns, and survival outcomes of intracranial ependymomas in pediatric patients. Higher tumor grade, infratentorial localization, and chemotherapy use was associated with worse OS, while larger tumor size correlated with lower mortality hazard. Disparities in care were identified, with uninsured patients experiencing prolonged LOS. These findings underscore the need for tailored treatment strategies based on patient and tumor characteristics and highlight the importance of addressing socioeconomic barriers to optimize outcomes for children with ependymomas.

Journal of Neurosurgery PediatricsVol. 34(5)
Mount Sinai Health System (US), SUNY Downstate Health Sciences University (US), Cornell University (US), Weill Cornell Medicine (US)
Good health and well-being
Openalex Percentile: Top 25%
Glioma Diagnosis and Treatment
0.88
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