Causal relationship between serum metabolites and idiopathic pulmonary fibrosis: Insights from a two-sample Mendelian randomization study
Our study identified 6 causal risks and 6 protective serum metabolites associated with IPF. Additionally, 2 metabolites were found to be involved in the pathogenesis of IPF through metabolic pathways, providing a new perspective for further understanding the metabolic pathway and the pathogenesis of IPF.
Authors
- Jun-Pei Hu
- Chang She (ORCID: https://orcid.org/0000-0002-1636-1885)
- Qiong‐Chao Zou
- Lihui Liang (ORCID: https://orcid.org/0009-0005-1213-9784)
- Yan Cao (ORCID: https://orcid.org/0000-0001-7866-1640)
- Zhengyu Liu (ORCID: https://orcid.org/0000-0003-4642-5955)
Institutions
- Hunan Normal University (CN)
- Hunan Provincial Center for Disease Control and Prevention (CN)
- Hunan Provincial People's Hospital (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e36125
- Citations
- 3
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- Development and Reform Commission of Hunan Province
- Health Commission of Hunan Province
- National Natural Science Foundation of China
- National Aerospace Science Foundation of China
- Science and Technology Program of Hunan Province