Balancing key stakeholder priorities and ethical principles to design a trial comparing intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy: FERN qualitative study
All three pregnancy management approaches for sFGR in MC twin pregnancy carry risks and benefits, and the ultimate goal for parents is to receive individualised care to achieve the best possible outcome for both twins. An RCT was not acceptable to parents or clinicians or seen as ethically appropriate. Alternative study designs should be considered to answer this important research question.
Authors
- Natasha Fenwick (ORCID: https://orcid.org/0000-0002-3232-163X)
- Richard Ashcroft (ORCID: https://orcid.org/0000-0001-6065-4717)
- Asma Khalil (ORCID: https://orcid.org/0000-0003-2802-7670)
- Andrew Sharp (ORCID: https://orcid.org/0000-0003-3396-7464)
- Tracy Karen Mitchell (ORCID: https://orcid.org/0000-0003-0014-8016)
- Smriti Prasad (ORCID: https://orcid.org/0000-0003-2329-4470)
- Shauna Leven
- M. Turner (ORCID: https://orcid.org/0000-0002-5299-8656)
- M Popa (ORCID: https://orcid.org/0009-0006-9237-4094)
- Christine Carnforth
Institutions
- University of Liverpool (GB)
- St George's, University of London (GB)
- City, University of London (GB)
- St George’s University Hospitals NHS Foundation Trust (GB)
Publication Details
- Journal
- BMJ Open
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1136/bmjopen-2023-080488
- Citations
- 1
- Primary Topic
- Assisted Reproductive Technology and Twin Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- National Institute for Health and Care Research
- Health Technology Assessment Programme