A conformable mathematical model of Ebola Virus Disease and its stability analysis

Ebola Virus Disease (EVD) is a viral hemorrhagic fever that affects humans and other primates. It is characterized by rapid virus spread in a short period of time. The disease has the potential to spread to many different regions of the world. In this paper, we have developed a modified mathematical model of the Ebola virus, adding the quarantine population as a control strategy. The quarantine population <i>F</i> and parameters <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub><mml:mrow><mml:mi>ρ</mml:mi></mml:mrow> <mml:mrow><mml:mn>3</mml:mn></mml:mrow> </mml:msub> </mml:math> represent the rate at which individuals enter the quarantine compartment, which is vital in controlling the virus spread within society. The conformable derivatives have been applied to the modified model to observe the behavior of individuals for fractional derivative values between 0.7 and 1. For a modified model, the threshold parameter ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub><mml:mrow><mml:mi>R</mml:mi></mml:mrow> <mml:mrow><mml:mn>0</mml:mn></mml:mrow> </mml:msub> </mml:math> ) has been determined using the Next-Generation Matrix (NGM) method. We have checked local and global stability at a disease-free equilibrium point using Routh-Herwitz (RH) criteria and Castillo-Chavez, respectively. Numerical results obtained through the Fourth-Order Runge Kutta Method (RK4) demonstrate, a decrease in the virus transmission rate after following the implementation of the quarantine strategy.

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Publication Details

Journal
Heliyon
Published
2024-08-01
DOI
https://doi.org/10.1016/j.heliyon.2024.e35818
Citations
7
Primary Topic
Viral Infections and Outbreaks Research
Type
article
Field-Weighted Citation Impact
2.72

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article

A conformable mathematical model of Ebola Virus Disease and its stability analysis

Sehrish Ramzan, Nadeem Abbas, Aqsa Nazir, Wasfı Shatanawi et al.
7 citations
Heliyon
Viral Infections and Outbreaks Research
2.72
article

A conformable mathematical model of Ebola Virus Disease and its stability analysis

Sehrish Ramzan, Nadeem Abbas, Aqsa Nazir, Wasfı Shatanawi, Syeda Alishwa Zanib
article en
7 citations

Abstract

Ebola Virus Disease (EVD) is a viral hemorrhagic fever that affects humans and other primates. It is characterized by rapid virus spread in a short period of time. The disease has the potential to spread to many different regions of the world. In this paper, we have developed a modified mathematical model of the Ebola virus, adding the quarantine population as a control strategy. The quarantine population <i>F</i> and parameters <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub><mml:mrow><mml:mi>ρ</mml:mi></mml:mrow> <mml:mrow><mml:mn>3</mml:mn></mml:mrow> </mml:msub> </mml:math> represent the rate at which individuals enter the quarantine compartment, which is vital in controlling the virus spread within society. The conformable derivatives have been applied to the modified model to observe the behavior of individuals for fractional derivative values between 0.7 and 1. For a modified model, the threshold parameter ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub><mml:mrow><mml:mi>R</mml:mi></mml:mrow> <mml:mrow><mml:mn>0</mml:mn></mml:mrow> </mml:msub> </mml:math> ) has been determined using the Next-Generation Matrix (NGM) method. We have checked local and global stability at a disease-free equilibrium point using Routh-Herwitz (RH) criteria and Castillo-Chavez, respectively. Numerical results obtained through the Fourth-Order Runge Kutta Method (RK4) demonstrate, a decrease in the virus transmission rate after following the implementation of the quarantine strategy.

HeliyonVol. 10(16)
Prince Sultan University (SA), Hashemite University (JO), National University of Modern Languages (PK), China Medical University (TW), Government College University, Faisalabad (PK), Riphah International University (PK), China Medical University Hospital (TW)
Prince Sultan University
Openalex Percentile: Top 9%
Viral Infections and Outbreaks Research
2.72
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