Oxytocin does not acutely improve glucose tolerance in men with type 2 diabetes
This outcome contrasts with the oxytocin-induced attenuation of early postprandial glucose excursions in normal-weight individuals, but is in line with the absence of respective effects in men with obesity. We conclude that insulin resistance in type 2 diabetes is associated with decreased sensitivity to the acute glucoregulatory effect of oxytocin in male individuals.
Authors
- Louise Fritsche (ORCID: https://orcid.org/0000-0003-0644-6161)
- Reiner Jumpertz‐von Schwarzenberg
- Tim Gruber (ORCID: https://orcid.org/0000-0001-6884-7046)
- Kοnstantinos Kantartzis (ORCID: https://orcid.org/0000-0002-0584-1138)
- Cristina García‐Cáceres (ORCID: https://orcid.org/0000-0001-6376-9448)
- Andreas Fritsche (ORCID: https://orcid.org/0000-0002-4987-1961)
- Hubert Preißl (ORCID: https://orcid.org/0000-0002-8859-4661)
- Nina Moszka
- Manfred Hallschmid (ORCID: https://orcid.org/0000-0002-0352-1106)
- Nina Goll
Institutions
- Van Andel Institute (US)
- Universität Hamburg (DE)
- Helmholtz Zentrum München (DE)
- LMU Klinikum (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- University Children's Hospital Tübingen (DE)
- Deutsches Diabetes-Zentrum e.V. (DE)
- German Center for Diabetes Research (DE)
- Heinrich Heine University Düsseldorf (DE)
- University of Tübingen (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2024-08-08
- DOI
- https://doi.org/10.1111/dom.15812
- Citations
- 1
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.64
Funders
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung