<scp>RNF135</scp> Promotes Human Osteosarcoma Cell Growth and Inhibits Apoptosis by Upregulating the <scp>PI3K</scp>/<scp>AKT</scp> Pathway

These results supported that RNF135 contributes to human OS development through PI3K/AKT-dependent mechanisms. Targeting RNF135 may provide a new therapeutic approach for treating this human malignancy.

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Publication Details

Journal
Cancer Reports
Published
2024-08-01
DOI
https://doi.org/10.1002/cnr2.2159
Primary Topic
Ubiquitin and proteasome pathways
Type
article
Field-Weighted Citation Impact
0.00

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article

RNF135 Promotes Human Osteosarcoma Cell Growth and Inhibits Apoptosis by Upregulating the PI3K/AKT Pathway

Yinglong Zhang, Guangze Song, Bingyao Chen, Xing Wei
Cancer Reports
Ubiquitin and proteasome pathways
article

RNF135 Promotes Human Osteosarcoma Cell Growth and Inhibits Apoptosis by Upregulating the PI3K/AKT Pathway

Yinglong Zhang, Guangze Song, Bingyao Chen, Xing Wei
article en

Abstract

These results supported that RNF135 contributes to human OS development through PI3K/AKT-dependent mechanisms. Targeting RNF135 may provide a new therapeutic approach for treating this human malignancy.

Cancer ReportsVol. 7(8)
Chinese PLA General Hospital (CN), Aerospace Center Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 88%
Ubiquitin and proteasome pathways
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