Association of pre-existing cardiovascular disease with administration of fluoropyrimidine chemotherapy in patients with gastrointestinal malignancies

GI cancer patients with all types of pre-existing CVD are less likely to receive fluoropyrimidine chemotherapy despite eligibility. This suggests widespread caution regarding administration of fluoropyrimidines across this population; further research is needed to assess whether such conservatism is justified.

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Publication Details

Journal
BMJ Oncology
Published
2024-08-01
DOI
https://doi.org/10.1136/bmjonc-2024-000323
Citations
1
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.42

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article

Association of pre-existing cardiovascular disease with administration of fluoropyrimidine chemotherapy in patients with gastrointestinal malignancies

Pinkie Chambers, Paul C. Lambert, Sally Vernon, Mark J. Rutherford et al.
1 citations
BMJ Oncology
Gastric Cancer Management and Outcomes
0.42
article

Association of pre-existing cardiovascular disease with administration of fluoropyrimidine chemotherapy in patients with gastrointestinal malignancies

Pinkie Chambers, Paul C. Lambert, Sally Vernon, Mark J. Rutherford, Catherine Welch, Kai‐Keen Shiu, Chengsheng Ju, Aderonke Abiodun, Charlotte Manisty, Lizz Paley, Mark de Belder, David Adlam, Jennifer Lai, Freya Tyrer, Li Wei, John Deanfield, Sarah Slater, Michael Peake
article en
1 citations

Abstract

GI cancer patients with all types of pre-existing CVD are less likely to receive fluoropyrimidine chemotherapy despite eligibility. This suggests widespread caution regarding administration of fluoropyrimidines across this population; further research is needed to assess whether such conservatism is justified.

BMJ OncologyVol. 3(1)
University College London Hospitals NHS Foundation Trust (GB), University of Leicester (GB), Barts Health NHS Trust (GB), Glenfield Hospital (GB), Karolinska Institutet (SE), Cancer Research UK Oxford Centre (GB), NIHR Research Delivery Network (GB), NIHR Leicester Biomedical Research Centre (GB), NHS England, University College London (GB)
Cancer Research UK, National Institute for Health and Care Research, British Heart Foundation, University College London, Barts Health NHS Trust
Good health and well-being
Openalex Percentile: Top 34%
Gastric Cancer Management and Outcomes
0.42
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