Development and Validation of a Novel Multiplex Real-Time PCR Assay for Rapid Detection of Carbapenemase Genes in Carbapenem-Resistant Enterobacterales Isolates and Clinical Samples
For clinical isolate detection, the multi-qPCR assay is comparable to Colloidal Gold, and superior to mCIMandeCIM and CDT; while for clinical samples detection, it also shows excellent performance. Therefore, the multi-qPCR assay has great potential for clinical diagnosis.
Authors
- Tianmeng Li (ORCID: https://orcid.org/0000-0003-1525-5674)
- Li Gu (ORCID: https://orcid.org/0000-0002-3318-3902)
- Ming Wei (ORCID: https://orcid.org/0000-0003-4035-5060)
- Jun Liu (ORCID: https://orcid.org/0000-0001-9515-3699)
- Shuai Wang (ORCID: https://orcid.org/0000-0002-9142-6095)
- Xi Chen (ORCID: https://orcid.org/0009-0003-4589-3025)
- Jing Wang
- Peng Wang (ORCID: https://orcid.org/0000-0002-5716-9937)
Institutions
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Beijing Anding Hospital (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2024-08-01
- DOI
- https://doi.org/10.2147/idr.s475630
- Citations
- 8
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Natural Science Foundation of China