The protein disulfide isomerase A3 and osteopontin axis promotes influenza‐induced lung remodelling
The PDIA3-SPP1 axis promotes post-influenza lung fibrosis in mice and that pharmacological inhibition of PDIA3 or SPP1 can treat virus-induced lung fibrotic sequela.
Authors
- R Chandrasekaran (ORCID: https://orcid.org/0000-0003-2166-4175)
- Joseph Walzer
- Clemente J. Britto (ORCID: https://orcid.org/0000-0002-1979-1151)
- Nirav Daphtary (ORCID: https://orcid.org/0000-0001-8794-5733)
- Jason H. T. Bates (ORCID: https://orcid.org/0000-0002-6062-6377)
- Amit Kumar (ORCID: https://orcid.org/0000-0002-7043-3798)
- Charles S. Dela Cruz (ORCID: https://orcid.org/0000-0002-5258-1797)
- Yvonne Janssen‐Heininger (ORCID: https://orcid.org/0000-0002-2735-8745)
- Anil Goud Jegga (ORCID: https://orcid.org/0000-0002-4881-7752)
- Vikas Anathy (ORCID: https://orcid.org/0000-0003-4288-912X)
- Matthew E. Poynter (ORCID: https://orcid.org/0000-0002-7578-4570)
- Morgan P. Carbajal
- M. Ruban
- John F. Alcorn (ORCID: https://orcid.org/0000-0001-5997-7711)
- Minara Aliyeva
- Z. Mark
- Dhemerson Souza DeLima
- Nicolas Chamberlain
Institutions
- University of Vermont (US)
- Cincinnati Children's Hospital Medical Center (US)
- University of Pittsburgh (US)
- Yale University (US)
- Children's Hospital of Pittsburgh (US)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2024-08-08
- DOI
- https://doi.org/10.1111/bph.16511
- Citations
- 3
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- University of Vermont
- National Institutes of Health